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10.1021/bi960737u 59 MojzikovaR.KoralkovaP.HolubD.ZidovaZ.PospisilovaD.CermakJ.et al (2014)

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Subsequent research indicated that genistein reduces oxidative stress and myogenic apoptosis through various mechanisms, including the regulation of ROS, lipid peroxidation, Bcl-2, and the apoptosis marker caspase-3 via the PI3K-Akt and ERK1/2 MAPK signaling pathways, with its effects remaining unaffected by estrogen receptor antagonists [28]